This is a complexdisease involving many steps with proper signalling pathways.
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It is a multifactorialdisorder with unclear etiology, affecting predominatly middle-aged women.
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Obesity is a chronic, complex, multifactorialdisorder with increasing prevalence in modern society.
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Cancer is a multifactorialdisorder involving multiplicity of interrelated signaling pathways and molecular targets.
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Adolescent idiopathic scoliosis (AIS) is a multifactorialdisorder characterized by a tridimensional deformation of the spine.
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Cleft palate most commonly occurs as a sporadic multifactorialdisorder with a clear but difficult to define genetic component.
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The potential for genetic screening of multifactorialdiseases, for example, cancers, should also be considered.
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In humans, the elucidation of the genetics underlying multifactorialdiseases such as pre-eclampsia remains complex.
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Overall genomic discoveries for preterm birth lag behind progress for many other multifactorialdiseases and traits.
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The heritability of most common, multifactorialdiseases is rather modest and known genetic effects account for a small part of it.
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Unfortunately, the use of these resources and their interpretation are not straightforward when applied to complex, multifactorialdiseases such as schizophrenia.
Uso de complex genetic disease en inglés
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Basic tenets of genetic counseling, complexgeneticdisease, and management of adults with genetic diagnoses also are discussed.
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T2DM is a complexgeneticdisease comprised of many metabolic disorders with a common phenotype of glucose intolerance.
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Background: Asthma is a complexgeneticdisease characterized by reversible intermittent airway obstruction and respiratory symptoms primarily caused by acute and chronic bronchial inflammation.
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Background: Asthma and allergic phenotypes are complexgeneticdiseases with known linkage to chromosome 5q.
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Future directions, particularly with regard to the study of common complexgeneticdiseases, are also described.
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This implies value in studying large well-characterized Ashkenazi populations to accelerate gene discovery in complexgeneticdiseases.
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As with many complexgeneticdiseases, genome scans for prostate cancer have given conflicting results, often failing to provide replication of previous findings.